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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERO1LB All Species: 35.76
Human Site: S212 Identified Species: 52.44
UniProt: Q86YB8 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86YB8 NP_063944.3 467 53543 S212 E N C F K P R S V Y R P L N P
Chimpanzee Pan troglodytes XP_001156276 467 53719 S212 E N C F K P R S V Y R P L N P
Rhesus Macaque Macaca mulatta XP_001103965 468 54383 T213 E N C F K P Q T I K R P L N P
Dog Lupus familis XP_546074 753 83528 S498 E N C F K P R S V Y R P L N P
Cat Felis silvestris
Mouse Mus musculus Q8R2E9 467 53500 S212 E N C F K P R S V Y R P L N P
Rat Rattus norvegicus Q8R4A1 464 54000 K209 I Y E E N C F K P Q T I Q R P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512742 679 76557 S426 E N C F K P R S V Y R P L N P
Chicken Gallus gallus XP_419554 467 53247 S212 E N C F K P R S V Y R P L N P
Frog Xenopus laevis Q6DD71 465 53720 A211 E N C F K P K A V Q R P L N P
Zebra Danio Brachydanio rerio Q7T3D1 489 56571 S205 E N C F K P Y S V N R P L N P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3A6 483 55641 Y223 H R I W K S I Y L E N C F G G
Honey Bee Apis mellifera XP_623933 471 55049 W215 G P S A H R I W K N I Y M E N
Nematode Worm Caenorhab. elegans Q7YTU4 478 55136 E207 V W K S I Y E E N C F K P D P
Sea Urchin Strong. purpuratus XP_796844 897 101920 N639 W S S I Y N E N C F R P E T P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C7S7 469 53812 T203 Q L N P E R Y T G Y T G P S A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SEY9 668 75589 S212 E N C F Q K S S F P K S A S L
Conservation
Percent
Protein Identity: 100 98.5 60 60.2 N.A. 94 59.3 N.A. 63.3 87.5 58.6 52.5 N.A. 46.1 49 40.7 25.8
Protein Similarity: 100 98.9 75 61.3 N.A. 96.5 74.5 N.A. 66.7 92.7 74.9 68 N.A. 63.9 65.8 59.2 35.9
P-Site Identity: 100 100 73.3 100 N.A. 100 6.6 N.A. 100 100 80 86.6 N.A. 6.6 0 6.6 20
P-Site Similarity: 100 100 93.3 100 N.A. 100 6.6 N.A. 100 100 93.3 86.6 N.A. 20 6.6 13.3 40
Percent
Protein Identity: N.A. N.A. N.A. 38.8 N.A. 28.5
Protein Similarity: N.A. N.A. N.A. 57.3 N.A. 39.6
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. 33.3
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. 53.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 0 0 0 7 0 0 0 0 7 0 7 % A
% Cys: 0 0 63 0 0 7 0 0 7 7 0 7 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % D
% Glu: 63 0 7 7 7 0 13 7 0 7 0 0 7 7 0 % E
% Phe: 0 0 0 63 0 0 7 0 7 7 7 0 7 0 0 % F
% Gly: 7 0 0 0 0 0 0 0 7 0 0 7 0 7 7 % G
% His: 7 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 7 7 7 0 13 0 7 0 7 7 0 0 0 % I
% Lys: 0 0 7 0 63 7 7 7 7 7 7 7 0 0 0 % K
% Leu: 0 7 0 0 0 0 0 0 7 0 0 0 57 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 0 63 7 0 7 7 0 7 7 13 7 0 0 57 7 % N
% Pro: 0 7 0 7 0 57 0 0 7 7 0 63 13 0 75 % P
% Gln: 7 0 0 0 7 0 7 0 0 13 0 0 7 0 0 % Q
% Arg: 0 7 0 0 0 13 38 0 0 0 63 0 0 7 0 % R
% Ser: 0 7 13 7 0 7 7 50 0 0 0 7 0 13 0 % S
% Thr: 0 0 0 0 0 0 0 13 0 0 13 0 0 7 0 % T
% Val: 7 0 0 0 0 0 0 0 50 0 0 0 0 0 0 % V
% Trp: 7 7 0 7 0 0 0 7 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 7 7 13 7 0 44 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _